Collagen is too large a molecule to absorb through the skin, but this moisturizer is still fantastic. It is super lightweight, and perfect to use before applying makeup. I wear mineral makeup, and I have found that applying the mist about fifteen minutes before I apply my foundation powder works wonders for my overall complexion. The mister is nice for even application, just be careful to hold the bottle a decent distance from your face so that it doesn't concentrate all in one area. It is one of my favorite cosmetic products.